NCT00000176COMPLETEDPhase 3This is a three-year study to determine if estrogens can prevent memory loss and Alzheimer's disease in women with a family history of Alzheimer's disease.
Inclusion Criteria: * Healthy women 65 or older with a family history of memory problems not currently on estrogen. Exclusion Criteria: * Significant neurological impairment * Current estrogen use * History of breast cancer