NCT00194025COMPLETEDResults postedPhase 4The purpose of this research study is to analyze the effectiveness and tolerability of a medication, valproate ( Depakote and Depakote ER), in individuals age 50 years and older who have schizophrenia.
Inclusion Criteria: * Must have a diagnosis of schizophrenia as confirmed by the MINI * Must be on antipsychotic medication * Must be age 50 year or older * Must be capable of providing written informed consent for study participation. In situations where individuals have guardians of person, guardian and subject must both provide written consent; and * Must live in the Northeast Ohio area. Exclusion Criteria: * A primary psychiatric DSM Axis I diagnosis other than schizophrenia * Actively abusing substances; or * Medically unstable.