The purpose of this study is to determine the sensitivity of Molecular Breast Imaging (MBI) relative to MRI of the breast in patients undergoing MRI for a clinical concern, or abnormal diagnostic mammogram and/or ultrasound study.
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Inclusion Criteria: * This study will include a population of women aged 25 or older who are scheduled for a breast MRI examination at MAYO CLINIC ROCHESTER. * Patients must not be lactating or pregnant. * All women of child-bearing potential must have had a negative urine pregnancy test result within 2 days prior to the MBI study. * women who are scheduled for a breast MRI examination for a clinical concern, problem solving or for further evaluation of invasive breast cancer (e.g. pre-operative staging of known breast cancer). Exclusion Criteria: * They are unable to understand and sign the consent form * They are pregnant or lactating * They are physically unable to sit upright and still for 40 minutes. * The breast MRI is for screening purposes or to determine the status of breast augmentation. * They have undergone breast surgery within the previous year