The purpose of this study is to investigate the clinical utility of renal denervation for the treatment of refractory hypertension.
Inclusion Criteria: * Systolic blood pressure of 160 mmHg or greater * On 3 or more antihypertensive medications * eGFR \>= 45 mL/min Exclusion Criteria: * Renal artery abnormalities * Known secondary hypertension attributable to a cause other than sleep apnea * MI, angina, CVA within 6 months * Type 1 diabetes * Others