A randomized, double blind, placebo-controlled pilot study on the efficacy of Passiflora incarnata L. in an acute stressful situation
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Inclusion Criteria: * Provide written informed consent; * Healthy male and female subjects * Non-smoker; * Age 25 to 45 years; * BMI ≥ 19 to ≤ 30 kg/m2 Exclusion Criteria: * Any known allergies to the test substance; * Any known addiction to drugs, alcohol or positive results in the drug screening test; * Any serious general illness, ongoing or within the last 12 months; * Any febrile illness (\> 24 hrs.) within 7 days prior to treatment; * Any antibiotics for the last four weeks before study inclusion; * Diabetes mellitus; * Known heart disease, hypertension, kidney disease, significant respiratory disease, epilepsy, or rheumatoid arthritis; * Known immunologic or infectious disease (e.g. hepatitis, tuberculosis, HIV or AIDS) which could place the subject at risk or interfere with the accuracy of the study results; * Pregnancy or lactating; * Current participation or participation in any type of clinical study in the past week; * Current or past participation in a TSST study; * Employees of the Sponsor or the CRO; * Any other medication that, in the opinion of the Investigator is likely to affect their response to treatment; * Clinically relevant abnormalities in physical examinations, vital signs, clinical chemistry, or haematology as judged by the Investigator; * Any other condition the Investigator or their duly assigned representatives believes may affect the ability of the individual to complete the study or the interpretation of the study results.