COMPLETEDN/A

Early Diagnosis of Small Pulmonary Nodules by Multi-omics Sequencing

Analyse immune repertoire and genetic mutations of benign and malignant pulmonary nodule，and evaluate peripheral blood detection for identifying nature of pulmonary nodule.

Sponsor

Peking University People's Hospital

Enrollment

100 participants

Sites

1 locations

Start Date

October 2017

Completion

July 2018

CarcinomaNon-small-cell Lung CancerLung Neoplasm

Enrollment & Timeline

Completed

Target N

100

participants

Sites

locations

Duration

14 months

total trial span

Rate

pts/month needed

At 1 sites, each site needs to enroll approximately 7.0 patients/month to hit the enrollment target on schedule.

View on ClinicalTrials.gov

Ask AI

Primary Outcomes

The sensitivity and specificity of combining peripheral plasma circulating tumor DNA and white cell immuno-sequencing in diagnosis of early stage non-small cell lung cancer

6 months

Ask AI

Multi-Source Intelligencefrom PubMed · FDA FAERS · WHO ICTRP

Multiomics Analysis Reveals Distinct Immunogenomic Features of Lung Cancer with Ground-Glass Opacity.

Chen Kezhong, Bai Jing, Reuben Alexandre et al.American journal of respiratory and critical care medicine2021

DOI PubMed

PubMed/NCBI (daily updates) FDA FAERS (quarterly updates) WHO ICTRP (weekly updates)

Ask AI

Fetching protocol from ClinicalTrials.gov…

COMPLETEDN/A

Early Diagnosis of Small Pulmonary Nodules by Multi-omics Sequencing

Analyse immune repertoire and genetic mutations of benign and malignant pulmonary nodule，and evaluate peripheral blood detection for identifying nature of pulmonary nodule.

Sponsor

Peking University People's Hospital

Enrollment

100 participants

Sites

1 locations

Start Date

October 2017

Completion

July 2018

CarcinomaNon-small-cell Lung CancerLung Neoplasm

Enrollment & Timeline

Completed

Target N

100

participants

Sites

locations

Duration

14 months

total trial span

Rate

pts/month needed

At 1 sites, each site needs to enroll approximately 7.0 patients/month to hit the enrollment target on schedule.

View on ClinicalTrials.gov

Ask AI

Primary Outcomes

The sensitivity and specificity of combining peripheral plasma circulating tumor DNA and white cell immuno-sequencing in diagnosis of early stage non-small cell lung cancer

6 months

Ask AI

Multi-Source Intelligencefrom PubMed · FDA FAERS · WHO ICTRP

Multiomics Analysis Reveals Distinct Immunogenomic Features of Lung Cancer with Ground-Glass Opacity.

Chen Kezhong, Bai Jing, Reuben Alexandre et al.American journal of respiratory and critical care medicine2021

DOI PubMed

PubMed/NCBI (daily updates) FDA FAERS (quarterly updates) WHO ICTRP (weekly updates)

Ask AI

Eligibility

Min Age

18 Years

Sex

all

Healthy Volunteers

View full criteria

Inclusion Criteria:

1. Sign informed consent and consent to participate in this study;
2. Found small nodules in pulmonary by CT and prepare for surgery;

Exclusion Criteria:

1. Malignant tumor history within the past 5 years;
2. Receiving chemotherapy, radiotherapy or targeted therapy before surgery;
3. Histology confirmed not non-small cell lung cancer
4. No matching tissue or blood samplesUnqualified blood samples

Early Diagnosis of Small Pulmonary Nodules by Multi-omics Sequencing

Enrollment & Timeline

Primary Outcomes

Multi-Source Intelligencefrom PubMed · FDA FAERS · WHO ICTRP

Early Diagnosis of Small Pulmonary Nodules by Multi-omics Sequencing

Enrollment & Timeline

Primary Outcomes

Multi-Source Intelligencefrom PubMed · FDA FAERS · WHO ICTRP

Eligibility

Trial Sites (1)