A randomized clinical trial with two arms: irradiated women and non-irradiated women. Irradiated women are randomized to reconstruction with a latissimus Dorsi flap and an implant or a deep inferior epigastria perforator flap. Non-irradiated women are randomized to reconstruction with a thoracodorsal flap with an implant or with an expander and later a permanent implant in two stages.
Irradiated patients: Inclusion Criteria: * Age 18-60 * DIEP is technically possible * Unilateral mastectomy * BMI\<30 Exclusion Criteria: * Scars on abdomen or back * Bilateral mastectomy * Previous liposuction abdomen * 61 years of age or older Non-irradiated patients Inclusion Criteria: -\>18 years of age * Unilateral mastectomy * BMI\<30 Exclusion Criteria: * Bilateral mastectomy * extensive scars on thorax