This study evaluate Frailty syndrome (FS) as a common syndrome in patients with cirrhosis and it is an independent predictor of hospitalizations, falls and mortality. Identifying, treating and preventing FS can improve the prognosis and quality of life of these patients and reduce health costs.
Inclusion Criteria: * Male or female patients * Aged \>18 years old, with cirrhosis diagnosed by clinical, analytical and ultrasound criteria or liver biopsy * Conscious and oriented in time and space and able to understand and follow the indications of the study. Exclusion Criteria: * Liver cirrhosis with poor prognosis (MELD \[Model for End Stage Liver Disease\]\> 25) * Hepatocellular carcinoma or other active neoplastic disease * Expected survival \<6 months * Acute and/or chronic hepatic encephalopathy * Neurological disorder that hinders the performance of the tests * Active alcoholism in the previous 3 months * Severe comorbidities * Hospitalization in the previous month * Contraindications to exercise or probiotic treatment (immunosuppression) * Refusal to sign informed consent.