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Bacteriostatic Saline as a Local Anesthetic in Minor Eyelid Procedures | ClariTrial

NCT05294640COMPLETEDResults postedPhase 4

Bacteriostatic Saline as a Local Anesthetic in Minor Eyelid Procedures

The investigators aim to assess whether bacteriostatic saline provides the same level of anesthesia as traditional local anesthesia while reducing pain associated with medication infusion in minor eyelid procedures

Sponsor

University of California, San Francisco

Enrollment

95 participants

Sites

1 locations

Start Date

May 2022

Completion

February 2023

Eyelid TumorEyelid BumpEyelid DeformityEyelid AbscessEyelid Boil

View on ClinicalTrials.gov

Primary Outcomes

Pain on Injection

5 minutes

Pain on a scale of 0-10 during injection process (0 being no pain, 10 being worst pain ever experienced). These will be patient-reported verbally and recorded immediately after injection.

Pain of Procedure

10 minutes

Pain on a scale of 0-10 during procedure (0 being no pain, 10 being worst pain ever experienced). These will be patient-reported verbally and recorded immediately after procedure.

Eligibility

Min Age

18 Years

Max Age

110 Years

Sex

all

Healthy Volunteers

Multi-Source Intelligencefrom PubMed · FDA FAERS · WHO ICTRP

Benzyl alcohol as an alternative local anesthetic.

Wilson L, Martin SAnnals of emergency medicine1999

Bacteriostatic saline containing benzyl alcohol decreases the pain associated with the injection of propofol.

Minogue Sean C, Sun Deidre AAnesthesia and analgesia2005

Comparison of 4 analgesic agents for venipuncture.

Patterson P, Hussa A A, Fedele K A et al.AANA journal2000

A double-blind randomized comparison of lidocaine and saline for cervical anesthesia.

Miller L, Jensen M P, Stenchever M AObstetrics and gynecology1996

Local Anesthesia Prior to Ultrasound-Guided Hip Joint Injections: A Double-Blind Randomized Controlled Trial of Bacteriostatic Saline versus Buffered Lidocaine.

Kruse Ryan C, Kindle Brett J, Wisniewski Steve et al.PM & R : the journal of injury, function, and rehabilitation2021

Increased patient comfort utilizing botulinum toxin type a reconstituted with preserved versus nonpreserved saline.

Kwiat David M, Bersani Thomas A, Bersani AdamOphthalmic plastic and reconstructive surgery2004

Bacteriostatic preserved saline for pain-free periocular injections: review.

Hunt Samantha Vicki, Malhotra RamanEye (London, England)2022

Comparison of three modified lidocaine solutions for use in eyelid anesthesia.

Yuen V H, Dolman P JOphthalmic plastic and reconstructive surgery1999

Less painful alternatives for local anesthesia.

Lugo-Janer G, Padial M, Sánchez J LThe Journal of dermatologic surgery and oncology1993

Intradermal lidocaine or bacteriostatic normal saline to decrease pain before intravenous catheter insertion: a meta-analysis.

Oman Kathleen S, Fink Regina, Kleiner Catherine et al.Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses2016

PubMed/NCBI (daily updates) FDA FAERS (quarterly updates) WHO ICTRP (weekly updates)