The goal of this observational study is to learn about the safety and efficacy of two-step radical prostatectomy in the treatment of low- to intermediate-risk prostate cancer patient with enlarged prostate and severe benign prostatic hyperplasia. The main question it aims to answer are: 1. Whether two-step prostatectomy is safe enough to decrease the surgical difficulty of these patients? 2. Whether the oncologic control is promising?
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Inclusion Criteria: 1. Diagnosed as prostate cancer pathologically by prostate biopsy 2. Evaluated as localized prostate cancer by imaging studies 3. Prostate volume\>70mL evaluated by transrectal ultrasonography or multi-parametric magnetic resonance imaging 4. Gleason score≤ 4+3=7 5. Preoperative PSA\<20ng/mL 6. Estimated survival\> 10 years； 7. Informed consent is obtained from the patient Exclusion Criteria: 1. The patient has received other therapy including radical radiotherapy, transurethral resection of the prostate, cryoablation, HIFU, etc. 2. Any contraindication of surgery or anaesthesia