RESTORE is a randomized clinical trial investigating the safety and feasibility of using EEG treatment targets (burst suppression vs. seizure suppression) for post-cardiac arrest refractory status epilepticus treatment.
No linked publications found in PubMed
Inclusion Criteria: 1. Age ≥18 years old 2. Non-traumatic, out-of-hospital cardiac arrest 3. Comatose on admission - defined as not following commands 4. Return of spontaneous circulation (ROSC) within less than 45 minutes 5. Admission to the intensive care unit 6. Diagnosis of post-cardiac arrest refractory status epilepticus confirmed with continuous EEG monitoring within 7 days from ROSC Exclusion Criteria: 1. Acute cerebral hemorrhage or infarction 2. Pregnancy 3. Prisoners