To develop strategies to identify postpartum women at risk for adverse cardiovascular outcomes and provide them with preventative therapies.
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Inclusion Criteria: * Pregnant women 18 years of age to 50 years of age * 10-24 weeks gestation at time of enrollment * Singleton pregnancy * Planning to deliver at a study site (UCSD or VUMC) Exclusion Criteria: * Inability to give informed consent * Intrauterine fetal demise * Fetal genetic or structural anomaly * Institutionalization for psychiatric disorder, mental deficiency or incarcerated * Active or history of malignancy requiring major surgery or systemic chemotherapy * Multi-fetal gestation or a twin demise at any gestational age * Known maternal or fetal chromosomal anomalies * Patients who plan to keep their placenta after delivery