RECRUITINGNA

Clinical Study on Laparoscopic Resection of Splenic Artery Aneurysm With Preservation of Spleen

In this study, researchers examined the changes in related indicators such as immune function, splenic vein,proper hepatic artery, and portal venous hemodynamics following laparoscopic resection of a splenic artery aneurysm. We determined the changes in these patient-related indicators after surgical treatment and whether these changes could improve patient outcomes.

Sponsor

Northern Jiangsu People's Hospital

Enrollment

10 participants

Sites

1 locations

Start Date

June 2025

Completion

June 2027

Splenic Artery AneurysmImmune FunctionHemodynamicslaparoscopic resection of splenic artery aneurysm with preservation of spleen

Enrollment & Timeline

Recruiting

Target enrollment (estimated)

Target N

participants

Sites

locations

Duration

2.0 years

total trial span

Jun 2025Month 12 of 24Jun 2027

50% of trial timeline elapsed12 months to primary endpoint

Enrollment target is estimated. ClinicalTrials.gov does not provide real-time enrollment progress.

View on ClinicalTrials.gov

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Multi-Source Intelligencefrom PubMed · FDA FAERS · WHO ICTRP

No linked publications found in PubMed

PubMed/NCBI (daily updates) FDA FAERS (quarterly updates) WHO ICTRP (weekly updates)

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Fetching protocol from ClinicalTrials.gov…

RECRUITINGNA

Clinical Study on Laparoscopic Resection of Splenic Artery Aneurysm With Preservation of Spleen

Sponsor

Northern Jiangsu People's Hospital

Enrollment

10 participants

Sites

1 locations

Start Date

June 2025

Completion

June 2027

Splenic Artery AneurysmImmune FunctionHemodynamicslaparoscopic resection of splenic artery aneurysm with preservation of spleen

Enrollment & Timeline

Recruiting

Target enrollment (estimated)

Target N

participants

Sites

locations

Duration

2.0 years

total trial span

Jun 2025Month 12 of 24Jun 2027

50% of trial timeline elapsed12 months to primary endpoint

Enrollment target is estimated. ClinicalTrials.gov does not provide real-time enrollment progress.

View on ClinicalTrials.gov

Ask AI

Multi-Source Intelligencefrom PubMed · FDA FAERS · WHO ICTRP

No linked publications found in PubMed

PubMed/NCBI (daily updates) FDA FAERS (quarterly updates) WHO ICTRP (weekly updates)

Ask AI

Primary Outcomes

The immune function at 7 days after surgery

7 days

The level of the immune function(Complement C3; Complement C4; IgG; IgA; IgM;CD19;CD20;CD16;CD56;CD3;CD4) at 7 days after surgery.

The immune function at 1 month after surgery

1 month

The level of the immune function(Complement C3; Complement C4; IgG; IgA; IgM;CD19;CD20;CD16;CD56;CD3;CD4) at 1 month after surgery.

The immune function at 3 months after surgery

3 months

The level of the immune function(Complement C3; Complement C4; IgG; IgA; IgM;CD19;CD20;CD16;CD56;CD3;CD4) at 3 months after surgery.

The immune function at 6 months after surgery

6 months

The level of the immune function(Complement C3; Complement C4; IgG; IgA; IgM;CD19;CD20;CD16;CD56;CD3;CD4) at 6 months after surgery.

The immune function at 12months after surgery

12months

The level of the immune function(Complement C3; Complement C4; IgG; IgA; IgM;CD19;CD20;CD16;CD56;CD3;CD4) at 12months after surgery.

Routine blood tests (Erythrocyte Count; Hemoglobins; Red Cell Distribution Width; White Blood Cell Count; Neutrophils; Lymphocytes; Monocytes; Eosinophils; Basophils; Platelet Count; Mean Platelet Volume; Blood Platelet) at 1 month postoperatively.

1 month

3 months

6 months

12 months

Hemodynamics (Vascular Diameter; Blood Flow Velocity) of the splenic vein,proper hepatic artery,and portal vein at 1 month postoperatively.

1 month

Hemodynamics (Vascular Diameter; Blood Flow Velocity) of the splenic vein,proper hepatic artery,and portal vein at 3 months postoperatively.

3 months

Hemodynamics (Vascular Diameter; Blood Flow Velocity) of the splenic vein,proper hepatic artery,and portal vein at 6 months postoperatively.

6 months

Hemodynamics (Vascular Diameter; Blood Flow Velocity) of the splenic vein,proper hepatic artery,and portal vein at 12 months postoperatively.

12 months

Thrombosis in the Portal Venous System.

1 month

Thrombosis in the Portal Venous System.

3 months

Thrombosis in the Portal Venous System.

6 months

Thrombosis in the Portal Venous System.

12 months

Eligibility

Min Age

18 Years

Sex

all

Healthy Volunteers

View full criteria

Inclusion Criteria:

* Asymptomatic splenic artery aneurysms with a diameter\>2 cm,ruptured splenic artery aneurysms,and splenic artery aneurysms with a diameter increase\>0.5 cm/year.

Aneurysm located in the main trunk of the splenic artery. Informed consent to participate in the study.

Exclusion Criteria:

* Patients with malignancies Hepatic cirrhosis with portal hypertension peptic ulcer disease Recent peptic ulcer disease History of Hemorrhagic stroke Pregnancy hematological diseases Uncontrolled Hypertension Human immunodeficiency virus (HIV) infection

Ask AI

Clinical Study on Laparoscopic Resection of Splenic Artery Aneurysm With Preservation of Spleen

Enrollment & Timeline

Multi-Source Intelligencefrom PubMed · FDA FAERS · WHO ICTRP

Clinical Study on Laparoscopic Resection of Splenic Artery Aneurysm With Preservation of Spleen

Enrollment & Timeline

Multi-Source Intelligencefrom PubMed · FDA FAERS · WHO ICTRP

Primary Outcomes

Eligibility

Trial Sites (1)