This study aims to fill knowledge gaps regarding microvascular perfusion and pressor response to stress among patients with history of spontaneous coronary artery dissection (SCAD) using stress contrast echocardiography.
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Inclusion Criteria: * Adult \>18 years old * Patient has a history of spontaneous coronary artery dissection (SCAD) OR patient is healthy with no significant medical history Exclusion Criteria: * Unable to give consent * Allergic or have a history of adverse reaction to dobutamine, the Definity® ultrasound enhancing agent, or atropine. * Has a known or suspected hypersensitivity to perflutren and therefore cannot be given Definity®. * Pregnant. * Unable to interrupt breastfeeding. * Within 3 months of a heart attack. * Severe aortic stenosis. * Severe, uncontrolled hypertension (\>200/110 mmHg at baseline).