NCT07406659RECRUITINGNA

Different Inspiratory Muscle Trainings in Patients With COPD

COPD is one of the most life-threatening pulmonary diseases. According to the World Health Organization, it is expected to rise to the third leading cause of death by 2030. Smoking is the most significant contributing factor. COPD reduces lung volumes and causes dyspnea. Over time, respiratory muscle weakness develops, leading to hypercapnia, dyspnea, nocturnal oxygen desaturation, and decreased exercise performance. Pulmonary rehabilitation is the most important component of COPD treatment. Respiratory muscle training should be a mandatory component of the pulmonary rehabilitation program. Combining inspiratory muscle training with functional exercises allows the focus to be on respiratory muscle functions beyond the task of breathing. The purpose of this study was to investigate the effects of Functional Inspiratory Muscle Training on the course of the disease.

Sponsor

University of Yalova

Enrollment

51 participants

Sites

1 locations

Start Date

March 2026

Completion

October 2026

Chronic Obstructive Pulmonary DiseaseBasic Inspiratory Muscle TrainingFunctional Inspiratory Muscle TrainingControl

View on ClinicalTrials.gov

Primary Outcomes

Dyspnea Assessment

Baseline and through study completion, an average of 8 weeks

Modified Medical Research Council -mMRC: The mMRC used for dyspnea assessment consists of five stages. Stage 0 represents mild dyspnea, and Stage 4 represents severe dyspnea (Bestall et al., 1999).

COPD Assesment Test

Baseline and through study completion, an average of 8 weeks

COPD Assessment Test (CAT): The test consists of eight questions that examine cough, phlegm, shortness of breath, home and outdoor difficulties, sleep, and fatigue parameters. The maximum score is 40. As the score increases, symptoms worsen. The validity and reliability of the Turkish version was conducted by Yorgancıoğlu et al. (Yorgancioglu, 2012).

Pulmonary Function Testing

Baseline and through study completion, an average of 8 weeks

Measurements are taken with a portable spirometer (Cosmed Pony FX, Cosmed, Rome, Italy) while the patient is in a seated position. Forced expiratory volume in one second (FEV1) is measured (Miller et al., 2005).

Pulmonary Function Testing

Baseline and through study completion, an average of 8 weeks

Measurements are taken with a portable spirometer (Cosmed Pony FX, Cosmed, Rome, Italy) while the patient is in a seated position. Forced vital capacity (FVC) is measured (Miller et al., 2005).

Pulmonary Function Testing

Multi-Source Intelligencefrom PubMed · FDA FAERS · WHO ICTRP

Inspiratory muscle training, with or without concomitant pulmonary rehabilitation, for chronic obstructive pulmonary disease (COPD).

Ammous Omar, Feki Walid, Lotfi Tamara et al.The Cochrane database of systematic reviews2023

Different Inspiratory Muscle Trainings in Patients With COPD

Primary Outcomes

Multi-Source Intelligencefrom PubMed · FDA FAERS · WHO ICTRP

Different Inspiratory Muscle Trainings in Patients With COPD

Primary Outcomes

Multi-Source Intelligencefrom PubMed · FDA FAERS · WHO ICTRP

Eligibility

Trial Sites (1)