The aim of this thesis; To define sarcopenia in knee osteoarthritis with ultrasonography and to evaluate changes in muscle structure in sarcopenia after isokinetic exercise application ultrasonographically. The investigators will evaluate the effect of isokinetic exercise therapy in sarcopenic patients with knee osteoarthritis with VAS (Visual Analog Scale) and WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index). Then, the hand grip strength will be evaluated with a dynamometer, and its effects on physical performance will be evaluated by 6 meters walking and chair rising tests.
Inclusion Criteria: * Among the 45-65 age group, 30 female patients diagnosed with knee osteoarthritis (Stage 1-2-3) and sarcopenia together * Among the 45-65 age group, 30 females without osteoarthritis and sarcopenia will be included in the study as the control group. Exclusion Criteria: * Diabetes Mellitus, * Severe Coronary Artery Disease / Congestive Heart Failure, * Severe Liver Failure, * Neuromuscular disease, * Lower extremity surgery, * Rheumatological disease, * Those who use walking aids