The goal of this observational study is to determine whether the secreted protein QSOX1 can be used as a molecular marker for early rapid diagnosis and accurate treatment of colon cancer.
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Inclusion Criteria: * Colon cancer was confirmed by colonoscopic pathology. * No local or systemic treatment was performed before operation. * Complete clinical data. Exclusion Criteria: * Combined with benign diseases of colon, such as ulcerative colitis, colon adenoma and colon polyp. * Other tumors other than colon cancer.