Prospective observational registry for an adolescent cohort with AD under the care of a dermatology provider. Approximately 1500 subjects and 75 clinical sites in North America and select European countries will be recruited to participate with no defined upper limit for either target.
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Inclusion Criteria:
* To be eligible to participate in this registry, an individual must meet all the following criteria:
1. Has been diagnosed with moderate to severe atopic dermatitis by a dermatologist or a qualified dermatology practitioner.
2. Is 12 - 15 years of age at the time of enrollment.
3. Meets one of the following conditions at the time of enrollment:
1. Has started taking a new Enrollment Eligible Medication within 6 months prior to the Enrollment visit. A new medication is a medication that the subject has never taken before.
OR
2. Is prescribed a new Enrollment Eligible Medication at the Enrollment visit. A new medication is a medication that the subject has never taken before.
Exclusion Criteria:
An individual who meets any of the following criteria will be excluded from participation in the registry:
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1. Is participating or planning to participate in a blinded clinical trial for an AD drug.