ClariTrial | Search Clinical Trials

Explore/Alzheimer's disease MCI prevention

Status

Phase

Pre-filtered to show active, later-stage trials with the strongest clinical signal.

26 results for “Alzheimer's disease MCI prevention” · Phase 3 · Phase 2

Page 1 of 2

UNKNOWN

Management of Mild Cognitive Impairment Patients With Extra Virgin Olive Oil - MICOIL

Phase 2Mild Cognitive Impairment

Freshly-Pressed Extra Virgin Olive Oilextra virgin olive oilmediterranean diet

Greek Alzheimer's Association and Related Disorders150 participants1 site · GreeceCompletes Feb 2018

Compare CT.gov Full analysis →

Recruiting

COMMETS- Combination MCI Metabolic Syndrome

Phase 2Alzheimer DiseaseMild Cognitive ImpairmentMetabolic Syndrome

SemaglutideIntranasal insulinSemaglutide placebo+1 more

Rutgers, The State University of New Jersey80 participants1 site · IsraelCompletes Dec 2027

Compare CT.gov Full analysis →

Completed

Results posted

Tau Imaging of Chronic Traumatic Encephalopathy

Phase 2Chronic Traumatic Encephalopathy

[F18]-T807[F18]-FlorbetapirMRI/MRS+1 more

Brigham and Women's Hospital30 participants2 sites · United StatesCompletes Sep 2016

Compare CT.gov Full analysis →

Active

Metformin in Alzheimer's Dementia Prevention

Phase 2Phase 3Mild Cognitive Impairment

Placebo oral tabletextended release metformin

Columbia University326 participants22 sites · United StatesCompletes Apr 2026

Compare CT.gov Full analysis →

Completed

Results posted

Valacyclovir for Mild Cognitive Impairment

Phase 2Mild Cognitive ImpairmentHerpes Simplex 1Herpes Simplex 2

Valacyclovir hydrochloride 500mg capletPlacebo sugar pill caplet

New York State Psychiatric Institute50 participants1 site · United StatesCompletes Oct 2024

Compare CT.gov Full analysis →

Completed

Results posted

Metformin in Amnestic Mild Cognitive Impairment

Phase 2Mild Cognitive Impairment

MetforminPlacebo

Columbia University80 participants1 site · United StatesCompletes Feb 2012

Compare CT.gov Full analysis →

Completed

Results posted

The Efficient Brain Study

Phase 2Metabolism - Cerebral Energy

Fermented Papaya PreparationGranulated Sugar

University of Florida30 participants1 site · United StatesCompletes Jul 2018

Compare CT.gov Full analysis →

UNKNOWN

Clinical Trial of a Low Protein Diet in Patients With Cognitive Impairment

Phase 1Phase 2Mild Cognitive ImpairmentMild DementiaFasting-Mimicking Diet

Fasting-Mimicking Diet ProlonADTM

University of Genova40 participants3 sites · ItalyCompletes Aug 2023

Compare CT.gov Full analysis →

Recruiting

ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults

Phase 2Cognitive DysfunctionAlzheimer DiseaseBlood-Brain Barrier

Alpha-Linolenic Acid (2.6 g/day)Placebo Control Group

Michal Schnaider Beeri, Ph.D.20 participants1 site · United StatesCompletes Apr 2027

Compare CT.gov Full analysis →

Completed

Results posted

The Synapse Project

Phase 2Alzheimer Disease

UCB-JMRI ScanPET Scan

University of Wisconsin, Madison100 participants1 site · United StatesCompletes Oct 2023

Compare CT.gov Full analysis →

Terminated

Results posted

Biomarker Qualification for Risk of Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease (AD) and Safety and Efficacy Evaluation of Pioglitazone in Delaying Its Onset

Phase 3Mild Cognitive Impairment Due to Alzheimer's Disease

PioglitazonePioglitazone placebo

Takeda3,494 participants55 sites · United States, Australia, GermanyCompletes Jul 2018

Compare CT.gov Full analysis →

Not Yet Recruiting

RQC for the Prevention of Alzheimer's Disease and Retinal Amyloid-β

Phase 2Alzheimer DiseaseMild Cognitive ImpairmentCognitive Decline

Resveratrol, Quercetin, and Curcumin (RQC)Curcumin

Zaparackas and Knepper LTD200 participants1 site · United StatesCompletes Jul 2027

Compare CT.gov Full analysis →

Completed

Randomized Trial of Low-dose Naproxen in Cognitively Intact Persons at Risk of Alzheimer's Dementia

Phase 2Alzheimer DiseaseCognitive Decline Due to Alzheimer DiseaseMild Cognitive Impairment Due to Alzheimer Disease

NaproxenPlacebo

Douglas Mental Health University Institute200 participants1 site · CanadaCompletes Mar 2017

Compare CT.gov Full analysis →

UNKNOWN

Curcumin and Yoga Therapy for Those at Risk for Alzheimer's Disease

Phase 2Mild Cognitive Impairment

Curcuminaerobic yoganon aerobic yoga+1 more

VA Office of Research and Development80 participants1 site · United StatesCompletes Mar 2020

Compare CT.gov Full analysis →

Completed

A Trial of Cilostazol in Patients With Mild Cognitive Impairment (COMCID)

Phase 2Mild Cognitive Impairment

CilostazolPlacebo

National Cerebral and Cardiovascular Center, Japan166 participants1 site · JapanCompletes Aug 2020

Compare CT.gov Full analysis →

1–15 of 26

Explore/Alzheimer's disease MCI prevention

Status

Phase

Pre-filtered to show active, later-stage trials with the strongest clinical signal.

26 results for “Alzheimer's disease MCI prevention” · Phase 3 · Phase 2

Page 1 of 2

UNKNOWN

Management of Mild Cognitive Impairment Patients With Extra Virgin Olive Oil - MICOIL

Phase 2Mild Cognitive Impairment

Freshly-Pressed Extra Virgin Olive Oilextra virgin olive oilmediterranean diet

Greek Alzheimer's Association and Related Disorders150 participants1 site · GreeceCompletes Feb 2018

Compare CT.gov Full analysis →

Recruiting

COMMETS- Combination MCI Metabolic Syndrome

Phase 2Alzheimer DiseaseMild Cognitive ImpairmentMetabolic Syndrome

SemaglutideIntranasal insulinSemaglutide placebo+1 more

Rutgers, The State University of New Jersey80 participants1 site · IsraelCompletes Dec 2027

Compare CT.gov Full analysis →

Completed

Results posted

Tau Imaging of Chronic Traumatic Encephalopathy

Phase 2Chronic Traumatic Encephalopathy

[F18]-T807[F18]-FlorbetapirMRI/MRS+1 more

Brigham and Women's Hospital30 participants2 sites · United StatesCompletes Sep 2016

Compare CT.gov Full analysis →

Active

Metformin in Alzheimer's Dementia Prevention

Phase 2Phase 3Mild Cognitive Impairment

Placebo oral tabletextended release metformin

Columbia University326 participants22 sites · United StatesCompletes Apr 2026

Compare CT.gov Full analysis →

Completed

Results posted

Valacyclovir for Mild Cognitive Impairment

Phase 2Mild Cognitive ImpairmentHerpes Simplex 1Herpes Simplex 2

Valacyclovir hydrochloride 500mg capletPlacebo sugar pill caplet

New York State Psychiatric Institute50 participants1 site · United StatesCompletes Oct 2024

Compare CT.gov Full analysis →

Completed

Results posted

Metformin in Amnestic Mild Cognitive Impairment

Phase 2Mild Cognitive Impairment

MetforminPlacebo

Columbia University80 participants1 site · United StatesCompletes Feb 2012

Compare CT.gov Full analysis →

Completed

Results posted

The Efficient Brain Study

Phase 2Metabolism - Cerebral Energy

Fermented Papaya PreparationGranulated Sugar

University of Florida30 participants1 site · United StatesCompletes Jul 2018

Compare CT.gov Full analysis →

UNKNOWN

Clinical Trial of a Low Protein Diet in Patients With Cognitive Impairment

Phase 1Phase 2Mild Cognitive ImpairmentMild DementiaFasting-Mimicking Diet

Fasting-Mimicking Diet ProlonADTM

University of Genova40 participants3 sites · ItalyCompletes Aug 2023

Compare CT.gov Full analysis →

Recruiting

ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults

Phase 2Cognitive DysfunctionAlzheimer DiseaseBlood-Brain Barrier

Alpha-Linolenic Acid (2.6 g/day)Placebo Control Group

Michal Schnaider Beeri, Ph.D.20 participants1 site · United StatesCompletes Apr 2027

Compare CT.gov Full analysis →

Completed

Results posted

The Synapse Project

Phase 2Alzheimer Disease

UCB-JMRI ScanPET Scan

University of Wisconsin, Madison100 participants1 site · United StatesCompletes Oct 2023

Compare CT.gov Full analysis →

Terminated

Results posted

Biomarker Qualification for Risk of Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease (AD) and Safety and Efficacy Evaluation of Pioglitazone in Delaying Its Onset

Phase 3Mild Cognitive Impairment Due to Alzheimer's Disease

PioglitazonePioglitazone placebo

Takeda3,494 participants55 sites · United States, Australia, GermanyCompletes Jul 2018

Compare CT.gov Full analysis →

Not Yet Recruiting

RQC for the Prevention of Alzheimer's Disease and Retinal Amyloid-β

Phase 2Alzheimer DiseaseMild Cognitive ImpairmentCognitive Decline

Resveratrol, Quercetin, and Curcumin (RQC)Curcumin

Zaparackas and Knepper LTD200 participants1 site · United StatesCompletes Jul 2027

Compare CT.gov Full analysis →

Completed

Randomized Trial of Low-dose Naproxen in Cognitively Intact Persons at Risk of Alzheimer's Dementia

Phase 2Alzheimer DiseaseCognitive Decline Due to Alzheimer DiseaseMild Cognitive Impairment Due to Alzheimer Disease

NaproxenPlacebo

Douglas Mental Health University Institute200 participants1 site · CanadaCompletes Mar 2017

Compare CT.gov Full analysis →

UNKNOWN

Curcumin and Yoga Therapy for Those at Risk for Alzheimer's Disease

Phase 2Mild Cognitive Impairment

Curcuminaerobic yoganon aerobic yoga+1 more

VA Office of Research and Development80 participants1 site · United StatesCompletes Mar 2020

Compare CT.gov Full analysis →

Completed

A Trial of Cilostazol in Patients With Mild Cognitive Impairment (COMCID)

Phase 2Mild Cognitive Impairment

CilostazolPlacebo

National Cerebral and Cardiovascular Center, Japan166 participants1 site · JapanCompletes Aug 2020

Compare CT.gov Full analysis →

1–15 of 26