ClariTrial | Search Clinical Trials

Explore/Arvinas

Status

Phase

26 results for “Arvinas”

Page 1 of 2

Completed

ARV-471 in Combination With Everolimus for the Treatment of Advanced or Metastatic ER+, HER2- Breast Cancer

Phase 1Breast Cancer

ARV-471 in combination with Everolimus

Arvinas Estrogen Receptor, Inc.32 participants9 sites · United States, SpainCompletes Jul 2024

Compare CT.gov Full analysis →

Recruiting

A Study to Evaluate ARV-806 in Adults With Advanced Cancer That Has the KRAS G12D Mutation

Phase 1Phase 2KRAS G12D MutationAdvanced Solid Cancer

ARV-806

Arvinas Inc.159 participants14 sites · United StatesCompletes Nov 2027

Compare CT.gov Full analysis →

Active

Results posted

A Study to Learn About a New Medicine Called Vepdegestrant (ARV-471, PF-07850327) in People Who Have Advanced Metastatic Breast Cancer

Phase 3Advanced Breast Cancer

ARV-471Fulvestrant

Pfizer624 participants312 sites · United States, Argentina, AustraliaCompletes Jan 2025

Compare CT.gov Full analysis →

Completed

A Study to Understand How the Study Medicine Called ARV-471 is Processed in Healthy Adults

Phase 1Healthy

[phenyl-14C]ARV-471[oxoisoindolin-14C]ARV-471

Pfizer12 participants1 site · United StatesCompletes Jul 2023

Compare CT.gov Full analysis →

Completed

Results posted

Trial of ARV-110 and Abiraterone in Participants With Metastatic Prostate Cancer

Phase 1Prostate Cancer Metastatic

BavdegalutamideAbiraterone

Arvinas Androgen Receptor, Inc.45 participants18 sites · United States, Canada, FranceCompletes Jul 2024

Compare CT.gov Full analysis →

Completed

A Study to Learn About the Study Medicine Called Vepdegestrant (ARV-471, PF-07850327) in People With ER+/HER2- Advanced Breast Cancer in China

Phase 1Breast Cancer

ARV-471

Pfizer9 participants3 sites · ChinaCompletes Mar 2024

Compare CT.gov Full analysis →

Active

Results posted

A Study to Learn About the Vepdegestrant (ARV-471, PF-07850327) in People With ER+/HER2- Locally Advanced or Metastatic Breast Cancer (BC)

Phase 1Breast Neoplasms

vepdegestrant

Pfizer6 participants3 sites · JapanCompletes May 2023

Compare CT.gov Full analysis →

Completed

A Phase 1/2 Trial of ARV-471 Alone and in Combination With Palbociclib (IBRANCE®) in Patients With ER+/HER2- Locally Advanced or Metastatic Breast Cancer

Phase 1Phase 2Breast Cancer

ARV-471ARV-471 in combination with palbociclib (IBRANCE®)

Arvinas Estrogen Receptor, Inc.217 participants16 sites · United StatesCompletes Sep 2024

Compare CT.gov Full analysis →

Recruiting

A Study to Learn How the Body Processes the Study Medicine Called Vepdegestrant in People With Loss of Liver Function

Phase 1Healthy Participants

vepdegestrant

Pfizer24 participants4 sites · United StatesCompletes Dec 2026

Compare CT.gov Full analysis →

Active

TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer (Sub-Study B)

Phase 1Phase 2Breast Cancer

ARV-471Ribociclib

Pfizer20 participants29 sites · United States, Canada, ItalyCompletes Dec 2026

Compare CT.gov Full analysis →

Recruiting

A Study of ARV-393 in Relapsed/Refractory Non-Hodgkin Lymphoma.

Phase 1Relapsed/Refractory (R/R) Mature B Cell Non Hodgkin Lymphoma (NHL)Relapsed/Refractory (R/R) Angioimmunoblastic T-cell Lymphoma (AITL)

ARV-393Glofitamab

Arvinas Inc.255 participants17 sites · United States, Canada, DenmarkCompletes Mar 2028

Compare CT.gov Full analysis →

Completed

A Study to Learn How a Tablet Compared With an IV Infusion of the Study Medicine Called Vepdegestrant is Taken up Into the Blood in Healthy Adults

Phase 1Healthy Participants

Vepdegestrant (Reference)Vepdegestrant (Test)

Pfizer10 participants2 sites · NetherlandsCompletes May 2025

Compare CT.gov Full analysis →

Completed

A Study to Learn If the Study Medicine Esomeprazole Changes How the Body Processes the Other Study Medicine Vepdegestrant

Phase 1Healthy

vepdegestrantesomeprazole

Pfizer12 participants1 site · United StatesCompletes May 2024

Compare CT.gov Full analysis →

Completed

A Study to Understand the Effects of Carbamazepine on How Vepdegestrant is Processed in Healthy Participants

Phase 1Healthy Participants

VepdegestrantCarbamazepine

Pfizer12 participants1 site · BelgiumCompletes Oct 2023

Compare CT.gov Full analysis →

Active

TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer. (Sub-Study C)

Phase 1Phase 2Breast Cancer

vepdegestrantSamuraciclib

Pfizer11 participants21 sites · United States, Belgium, FranceCompletes Dec 2026

Compare CT.gov Full analysis →

1–15 of 26

Explore/Arvinas

Status

Phase

26 results for “Arvinas”

Page 1 of 2

Completed

ARV-471 in Combination With Everolimus for the Treatment of Advanced or Metastatic ER+, HER2- Breast Cancer

Phase 1Breast Cancer

ARV-471 in combination with Everolimus

Arvinas Estrogen Receptor, Inc.32 participants9 sites · United States, SpainCompletes Jul 2024

Compare CT.gov Full analysis →

Recruiting

A Study to Evaluate ARV-806 in Adults With Advanced Cancer That Has the KRAS G12D Mutation

Phase 1Phase 2KRAS G12D MutationAdvanced Solid Cancer

ARV-806

Arvinas Inc.159 participants14 sites · United StatesCompletes Nov 2027

Compare CT.gov Full analysis →

Active

Results posted

A Study to Learn About a New Medicine Called Vepdegestrant (ARV-471, PF-07850327) in People Who Have Advanced Metastatic Breast Cancer

Phase 3Advanced Breast Cancer

ARV-471Fulvestrant

Pfizer624 participants312 sites · United States, Argentina, AustraliaCompletes Jan 2025

Compare CT.gov Full analysis →

Completed

A Study to Understand How the Study Medicine Called ARV-471 is Processed in Healthy Adults

Phase 1Healthy

[phenyl-14C]ARV-471[oxoisoindolin-14C]ARV-471

Pfizer12 participants1 site · United StatesCompletes Jul 2023

Compare CT.gov Full analysis →

Completed

Results posted

Trial of ARV-110 and Abiraterone in Participants With Metastatic Prostate Cancer

Phase 1Prostate Cancer Metastatic

BavdegalutamideAbiraterone

Arvinas Androgen Receptor, Inc.45 participants18 sites · United States, Canada, FranceCompletes Jul 2024

Compare CT.gov Full analysis →

Completed

A Study to Learn About the Study Medicine Called Vepdegestrant (ARV-471, PF-07850327) in People With ER+/HER2- Advanced Breast Cancer in China

Phase 1Breast Cancer

ARV-471

Pfizer9 participants3 sites · ChinaCompletes Mar 2024

Compare CT.gov Full analysis →

Active

Results posted

A Study to Learn About the Vepdegestrant (ARV-471, PF-07850327) in People With ER+/HER2- Locally Advanced or Metastatic Breast Cancer (BC)

Phase 1Breast Neoplasms

vepdegestrant

Pfizer6 participants3 sites · JapanCompletes May 2023

Compare CT.gov Full analysis →

Completed

A Phase 1/2 Trial of ARV-471 Alone and in Combination With Palbociclib (IBRANCE®) in Patients With ER+/HER2- Locally Advanced or Metastatic Breast Cancer

Phase 1Phase 2Breast Cancer

ARV-471ARV-471 in combination with palbociclib (IBRANCE®)

Arvinas Estrogen Receptor, Inc.217 participants16 sites · United StatesCompletes Sep 2024

Compare CT.gov Full analysis →

Recruiting

A Study to Learn How the Body Processes the Study Medicine Called Vepdegestrant in People With Loss of Liver Function

Phase 1Healthy Participants

vepdegestrant

Pfizer24 participants4 sites · United StatesCompletes Dec 2026

Compare CT.gov Full analysis →

Active

TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer (Sub-Study B)

Phase 1Phase 2Breast Cancer

ARV-471Ribociclib

Pfizer20 participants29 sites · United States, Canada, ItalyCompletes Dec 2026

Compare CT.gov Full analysis →

Recruiting

A Study of ARV-393 in Relapsed/Refractory Non-Hodgkin Lymphoma.

Phase 1Relapsed/Refractory (R/R) Mature B Cell Non Hodgkin Lymphoma (NHL)Relapsed/Refractory (R/R) Angioimmunoblastic T-cell Lymphoma (AITL)

ARV-393Glofitamab

Arvinas Inc.255 participants17 sites · United States, Canada, DenmarkCompletes Mar 2028

Compare CT.gov Full analysis →

Completed

A Study to Learn How a Tablet Compared With an IV Infusion of the Study Medicine Called Vepdegestrant is Taken up Into the Blood in Healthy Adults

Phase 1Healthy Participants

Vepdegestrant (Reference)Vepdegestrant (Test)

Pfizer10 participants2 sites · NetherlandsCompletes May 2025

Compare CT.gov Full analysis →

Completed

A Study to Learn If the Study Medicine Esomeprazole Changes How the Body Processes the Other Study Medicine Vepdegestrant

Phase 1Healthy

vepdegestrantesomeprazole

Pfizer12 participants1 site · United StatesCompletes May 2024

Compare CT.gov Full analysis →

Completed

A Study to Understand the Effects of Carbamazepine on How Vepdegestrant is Processed in Healthy Participants

Phase 1Healthy Participants

VepdegestrantCarbamazepine

Pfizer12 participants1 site · BelgiumCompletes Oct 2023

Compare CT.gov Full analysis →

Active

TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer. (Sub-Study C)

Phase 1Phase 2Breast Cancer

vepdegestrantSamuraciclib

Pfizer11 participants21 sites · United States, Belgium, FranceCompletes Dec 2026

Compare CT.gov Full analysis →

1–15 of 26