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Explore/cardiovascular heart disease

Status

Phase

Pre-filtered to show active, later-stage trials with the strongest clinical signal.

580 results for “cardiovascular heart disease” · Recruiting · Phase 3 · Phase 2

Page 1 of 39

Recruiting

Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction - Coronary Computed Tomography Angiography Trial

Phase 3Cardiovascular Disease

OlpasiranPlacebo

Amgen406 participants40 sites · United States, Australia, CanadaCompletes Jun 2028

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Recruiting

Dapagliflozin and Endothelin Receptor Antagonism in Large Vessel Vasculitis (DERAIL-LVV)

Phase 2Large Vessel VasculitisGiant Cell Arteritis (GCA)Takayasu Arteritis

Bosentan and dapagliflozin

University of Edinburgh60 participants1 site · United KingdomCompletes Jul 2027

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Recruiting

The Effects of Hydroxychloroquine in Patients with Inflammatory Cardiomyopathy

Phase 2Phase 3Inflammatory CardiomyopathyMyocarditis

HydroxychloroquinePrednisolone

Tongji Hospital200 participants1 site · ChinaCompletes Sep 2024

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Recruiting

LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis

Phase 3Metabolic Dysfunction Associated Steatohepatitis

SurvodutidePlacebo matching survodutide

Boehringer Ingelheim1,590 participants438 sites · United States, Argentina, AustraliaCompletes Jun 2029

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Recruiting

Bromocriptine in Dilated Cardiomyopathy Among Women of Reproductive Age

Phase 3Dilated Cardiomyopathy

Bromocriptine mesylate plus standard GDMT

Jimma University112 participants1 site · EthiopiaCompletes May 2026

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Recruiting

Comparing Magnesium 2g Versus 4g Versus Placebo in the Incidence of Treating AFF RVR

Phase 3Tachycardia AtrialAtrial FibrillationAtrial Flutter With Rapid Ventricular Response

Magnesium Sulfate 2 GMagnesium Sulfate 4 GSaline

Wake Forest University Health Sciences153 participants1 site · United StatesCompletes Dec 2026

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Recruiting

tDCS for Post-Stroke Cognitive Impairment

Phase 2StrokeMild Cognitive Impairment

Transcranial Dirrect Current Stimulation

University of Oklahoma80 participants1 site · United StatesCompletes Jun 2026

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Recruiting

A Phase III Trial of HRS-1893 in Patients With Obstructive Hypertrophic Cardiomyopathy

Phase 3Obstructive Hypertrophic Cardiomyopathy

HRS-1893 TabletsHRS-1893 Placebo Tablets

Shandong Suncadia Medicine Co., Ltd.216 participants1 site · ChinaCompletes Sep 2026

Compare CT.gov Full analysis →

Recruiting

Comparative Study on the Mode of Action of Vicadrostat and Spironolactone on Protein Profiles and Renal Hemodynamic Effects (COMPARE-VS)

Phase 2CKDCardiovascular DiseasesHeart Failure

vicadrostat / empagliflozin combination 1Spironolactone (drug)

University Medical Center Groningen100 participants2 sites · NetherlandsCompletes Feb 2028

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Recruiting

Interstitial Photodynamic Therapy Following Palliative Radiotherapy in Treating Patients With Inoperable Malignant Central Airway Obstruction

Phase 1Phase 2Malignant Solid Neoplasm

Biospecimen CollectionComputed TomographyEndobronchial Ultrasound Bronchoscopy+6 more

Roswell Park Cancer Institute42 participants2 sites · United StatesCompletes Oct 2029

Compare CT.gov Full analysis →

Recruiting

Fetal Cerebrovascular Autoregulation in Congenital Heart Disease and Association With Neonatal Neurobehavior

Phase 2Phase 3Congenital Heart Disease in ChildrenHypoxiaNeurodevelopmental Disorders

Single ArmNeonatal Neurobehavioral Scale

University of Utah150 participants5 sites · United StatesCompletes Dec 2025

Compare CT.gov Full analysis →

Recruiting

A Research Study to Look at the Effect of Ziltivekimab on Plaque in the Blood Vessels of the Heart, Compared to Placebo, in People With a Heart Attack

Phase 3Myocardial Infarction

ZiltivekimabZiltivekimab Placebo

Novo Nordisk A/S332 participants20 sites · Austria, Denmark, ItalyCompletes Nov 2028

Compare CT.gov Full analysis →

Recruiting

A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants With Severe Alopecia Areata

Phase 3Alopecia Areata

UpadacitinibPlacebo

AbbVie1,500 participants268 sites · United States, Argentina, AustraliaCompletes Apr 2030

Compare CT.gov Full analysis →

Recruiting

Efficacy and Safety of Belimumab in the Treatment of Non-infectious Active Cryoglobulinemia Vasculitis Compared to Placebo. TRIBECA STUDY (Treatment nd BElimumab in Cryoglobulinemia Associated Vasculitis)

Phase 2VasculitisCryoglobulinemia

BelimumabPlacebo

Assistance Publique - Hôpitaux de Paris48 participants20 sites · FranceCompletes Apr 2025

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Recruiting

The Chronic Kidney Disease Adaptive Platform Trial Investigating Various Agents for Therapeutic Effect

Phase 3Chronic Kidney Diseases

FinerenonePlacebo Finerenone

The George Institute1,000 participants43 sites · Australia, India, New ZealandCompletes Aug 2028

Compare CT.gov Full analysis →

1–15 of 580

Explore/cardiovascular heart disease

Status

Phase

Pre-filtered to show active, later-stage trials with the strongest clinical signal.

580 results for “cardiovascular heart disease” · Recruiting · Phase 3 · Phase 2

Page 1 of 39

Recruiting

Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction - Coronary Computed Tomography Angiography Trial

Phase 3Cardiovascular Disease

OlpasiranPlacebo

Amgen406 participants40 sites · United States, Australia, CanadaCompletes Jun 2028

Compare CT.gov Full analysis →

Recruiting

Dapagliflozin and Endothelin Receptor Antagonism in Large Vessel Vasculitis (DERAIL-LVV)

Phase 2Large Vessel VasculitisGiant Cell Arteritis (GCA)Takayasu Arteritis

Bosentan and dapagliflozin

University of Edinburgh60 participants1 site · United KingdomCompletes Jul 2027

Compare CT.gov Full analysis →

Recruiting

The Effects of Hydroxychloroquine in Patients with Inflammatory Cardiomyopathy

Phase 2Phase 3Inflammatory CardiomyopathyMyocarditis

HydroxychloroquinePrednisolone

Tongji Hospital200 participants1 site · ChinaCompletes Sep 2024

Compare CT.gov Full analysis →

Recruiting

LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis

Phase 3Metabolic Dysfunction Associated Steatohepatitis

SurvodutidePlacebo matching survodutide

Boehringer Ingelheim1,590 participants438 sites · United States, Argentina, AustraliaCompletes Jun 2029

Compare CT.gov Full analysis →

Recruiting

Bromocriptine in Dilated Cardiomyopathy Among Women of Reproductive Age

Phase 3Dilated Cardiomyopathy

Bromocriptine mesylate plus standard GDMT

Jimma University112 participants1 site · EthiopiaCompletes May 2026

Compare CT.gov Full analysis →

Recruiting

Comparing Magnesium 2g Versus 4g Versus Placebo in the Incidence of Treating AFF RVR

Phase 3Tachycardia AtrialAtrial FibrillationAtrial Flutter With Rapid Ventricular Response

Magnesium Sulfate 2 GMagnesium Sulfate 4 GSaline

Wake Forest University Health Sciences153 participants1 site · United StatesCompletes Dec 2026

Compare CT.gov Full analysis →

Recruiting

tDCS for Post-Stroke Cognitive Impairment

Phase 2StrokeMild Cognitive Impairment

Transcranial Dirrect Current Stimulation

University of Oklahoma80 participants1 site · United StatesCompletes Jun 2026

Compare CT.gov Full analysis →

Recruiting

A Phase III Trial of HRS-1893 in Patients With Obstructive Hypertrophic Cardiomyopathy

Phase 3Obstructive Hypertrophic Cardiomyopathy

HRS-1893 TabletsHRS-1893 Placebo Tablets

Shandong Suncadia Medicine Co., Ltd.216 participants1 site · ChinaCompletes Sep 2026

Compare CT.gov Full analysis →

Recruiting

Comparative Study on the Mode of Action of Vicadrostat and Spironolactone on Protein Profiles and Renal Hemodynamic Effects (COMPARE-VS)

Phase 2CKDCardiovascular DiseasesHeart Failure

vicadrostat / empagliflozin combination 1Spironolactone (drug)

University Medical Center Groningen100 participants2 sites · NetherlandsCompletes Feb 2028

Compare CT.gov Full analysis →

Recruiting

Interstitial Photodynamic Therapy Following Palliative Radiotherapy in Treating Patients With Inoperable Malignant Central Airway Obstruction

Phase 1Phase 2Malignant Solid Neoplasm

Biospecimen CollectionComputed TomographyEndobronchial Ultrasound Bronchoscopy+6 more

Roswell Park Cancer Institute42 participants2 sites · United StatesCompletes Oct 2029

Compare CT.gov Full analysis →

Recruiting

Fetal Cerebrovascular Autoregulation in Congenital Heart Disease and Association With Neonatal Neurobehavior

Phase 2Phase 3Congenital Heart Disease in ChildrenHypoxiaNeurodevelopmental Disorders

Single ArmNeonatal Neurobehavioral Scale

University of Utah150 participants5 sites · United StatesCompletes Dec 2025

Compare CT.gov Full analysis →

Recruiting

A Research Study to Look at the Effect of Ziltivekimab on Plaque in the Blood Vessels of the Heart, Compared to Placebo, in People With a Heart Attack

Phase 3Myocardial Infarction

ZiltivekimabZiltivekimab Placebo

Novo Nordisk A/S332 participants20 sites · Austria, Denmark, ItalyCompletes Nov 2028

Compare CT.gov Full analysis →

Recruiting

A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants With Severe Alopecia Areata

Phase 3Alopecia Areata

UpadacitinibPlacebo

AbbVie1,500 participants268 sites · United States, Argentina, AustraliaCompletes Apr 2030

Compare CT.gov Full analysis →

Recruiting

Phase 2VasculitisCryoglobulinemia

BelimumabPlacebo

Assistance Publique - Hôpitaux de Paris48 participants20 sites · FranceCompletes Apr 2025

Compare CT.gov Full analysis →

Recruiting

The Chronic Kidney Disease Adaptive Platform Trial Investigating Various Agents for Therapeutic Effect

Phase 3Chronic Kidney Diseases

FinerenonePlacebo Finerenone

The George Institute1,000 participants43 sites · Australia, India, New ZealandCompletes Aug 2028

Compare CT.gov Full analysis →

1–15 of 580