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Explore/cardiovascular heart disease

Status

Phase

Pre-filtered to show active, later-stage trials with the strongest clinical signal.

583 results for “cardiovascular heart disease” · Recruiting · Phase 3 · Phase 2

Page 1 of 39

Recruiting

A Research Study Comparing CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Reduced/Mildly Reduced Ejection Fraction and Left Ventricular Hypertrophy

Phase 2Heart Failure

CDR132LPlacebo

Novo Nordisk A/S200 participants92 sites · Australia, Czechia, GermanyCompletes May 2027

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Recruiting

TIRzepatide for the Treatment of Obesity in Patients With Atrial Fibrillation

Phase 2Atrial FibrillationObesity

TirzepatidePlacebo

The Cleveland Clinic100 participants1 site · United StatesCompletes Dec 2026

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Recruiting

RiLuzole to Reduce Atrial FIb Study Using Holter Monitoring

Phase 2Atrial Fibrillation Paroxysmal

Riluzole 50 MG

University of Utah78 participants1 site · United StatesCompletes Oct 2024

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Recruiting

Endocalyx in Treatment Resistent Hypertension

Phase 2Treatment Resistant Hypertension

Endocalyx ProPlacebo

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)64 participants1 site · NetherlandsCompletes Dec 2027

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Recruiting

Aspirin-free Strategy With Ticagrelor in Patients With a Myocardial Infarction Treated Medically Alone

Phase 3NSTEMI - Non-ST Segment Elevation MISTEMI (ST Elevation MI)Myocardial Infarction

Ticagrelor + placeboTicagrelor + aspirin

Montreal Heart Institute2,570 participants1 site · CanadaCompletes Jan 2030

Compare CT.gov Full analysis →

Recruiting

An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)

Phase 3Cardiovascular Disease and Lipoprotein(a)

Pelacarsen (TQJ230)

Novartis Pharmaceuticals5,700 participants643 sites · United States, Argentina, AustraliaCompletes Jan 2030

Compare CT.gov Full analysis →

Recruiting

Effect of Glp-1 and Antidiabetic sgLT2 Agents for myoCardial infarcTion and Ultrasensitive Inflammatory Surveillance (GALACTUS Trial)

Phase 3Acute Myocardial Infarction With ST Elevation

Dapagliflozin 10 MG Oral TabletSemaglutide (Rybelsus®)

Instituto Mexicano del Seguro Social44 participants1 site · MexicoCompletes Aug 2026

Compare CT.gov Full analysis →

Recruiting

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

Phase 3Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8

Biospecimen CollectionBleomycin SulfateBrentuximab Vedotin+17 more

National Cancer Institute (NCI)1,875 participants407 sites · United States, Canada, Puerto RicoCompletes Apr 2031

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Recruiting

A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis

Phase 3Atopic Dermatitis

UpadacitinibDupilumab

AbbVie675 participants148 sites · United States, Argentina, AustraliaCompletes Jul 2030

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Recruiting

Rifampin-free Regimen Versus Rifampin-containing Regimen in the Treatment of Staphylococcal Prosthetic Valve Endocarditis

Phase 3Infective Endocarditis

Rifampin-free regimenRifampin containing regimen

Nantes University Hospital422 participants31 sites · FranceCompletes Dec 2030

Compare CT.gov Full analysis →

Recruiting

Comparison of Supra vs Infra Inguinal Fascia Iliaca Blocks for Spinal Positioning and Analgesia in Lower Limb Surgery

Phase 2Phase 3Post Operative AnalgesiaBradycardiaHypotension Drug-Induced

USG GUIDED SUPRA-INGUINAL FASCIA ILIACA BLOCKUSG GUIDED INFRA-INGUINAL FASCIA ILIACA BLOCK

Sahiwal medical college sahiwal60 participants1 site · PakistanCompletes Oct 2026

Compare CT.gov Full analysis →

Recruiting

DOR/TDF/3TC COmpared With BIC/FTC/TAF in ART-Naïve People Living With HIV and Overweight or Obesity

Phase 3HIV - Human Immunodeficiency VirusObesityOverweight and/or Obesity

DOR/3TC/TDFBIC/FTC/TAF

José Antonio Mata Marín306 participants1 site · MexicoCompletes Jun 2026

Compare CT.gov Full analysis →

Recruiting

Early Screening and Treatment of Heart Complication in Sickle Cell Disease

Phase 2Sickle Cell Disease

DeferoxamineDeferasiroxDeferiprone+2 more

Inova Health Care Services100 participants2 sites · United StatesCompletes Jun 2026

Compare CT.gov Full analysis →

Recruiting

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

Phase 3Heart Failure With Preserved Ejection FractionHeart Failure With Mildly Reduced Ejection FractionObesity

Maridebart cafraglutidePlacebo

Amgen5,056 participants628 sites · United States, Argentina, AustraliaCompletes Jun 2028

Compare CT.gov Full analysis →

Recruiting

Analysis of Growth Differentiation Factor 15 (GDF-15), Mid Regional proAdrenomedullin (MR proADM), and Persepsin Levels in Patient in Acute Coronary Syndrome Patients With Pneumonia, With or Without Influenza Vaccination

Phase 3Acute Coronary Syndromes (ACS)PneumoniaCOPD (Chronic Obstructive Pulmonary Disease)

Vaxigripantibiotic treatmentspercutaneus coronary intervention

University of Brawijaya60 participants1 site · IndonesiaCompletes Aug 2026

Compare CT.gov Full analysis →

1–15 of 583

Explore/cardiovascular heart disease

Status

Phase

Pre-filtered to show active, later-stage trials with the strongest clinical signal.

583 results for “cardiovascular heart disease” · Recruiting · Phase 3 · Phase 2

Page 1 of 39

Recruiting

A Research Study Comparing CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Reduced/Mildly Reduced Ejection Fraction and Left Ventricular Hypertrophy

Phase 2Heart Failure

CDR132LPlacebo

Novo Nordisk A/S200 participants92 sites · Australia, Czechia, GermanyCompletes May 2027

Compare CT.gov Full analysis →

Recruiting

TIRzepatide for the Treatment of Obesity in Patients With Atrial Fibrillation

Phase 2Atrial FibrillationObesity

TirzepatidePlacebo

The Cleveland Clinic100 participants1 site · United StatesCompletes Dec 2026

Compare CT.gov Full analysis →

Recruiting

RiLuzole to Reduce Atrial FIb Study Using Holter Monitoring

Phase 2Atrial Fibrillation Paroxysmal

Riluzole 50 MG

University of Utah78 participants1 site · United StatesCompletes Oct 2024

Compare CT.gov Full analysis →

Recruiting

Endocalyx in Treatment Resistent Hypertension

Phase 2Treatment Resistant Hypertension

Endocalyx ProPlacebo

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)64 participants1 site · NetherlandsCompletes Dec 2027

Compare CT.gov Full analysis →

Recruiting

Aspirin-free Strategy With Ticagrelor in Patients With a Myocardial Infarction Treated Medically Alone

Phase 3NSTEMI - Non-ST Segment Elevation MISTEMI (ST Elevation MI)Myocardial Infarction

Ticagrelor + placeboTicagrelor + aspirin

Montreal Heart Institute2,570 participants1 site · CanadaCompletes Jan 2030

Compare CT.gov Full analysis →

Recruiting

An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)

Phase 3Cardiovascular Disease and Lipoprotein(a)

Pelacarsen (TQJ230)

Novartis Pharmaceuticals5,700 participants643 sites · United States, Argentina, AustraliaCompletes Jan 2030

Compare CT.gov Full analysis →

Recruiting

Effect of Glp-1 and Antidiabetic sgLT2 Agents for myoCardial infarcTion and Ultrasensitive Inflammatory Surveillance (GALACTUS Trial)

Phase 3Acute Myocardial Infarction With ST Elevation

Dapagliflozin 10 MG Oral TabletSemaglutide (Rybelsus®)

Instituto Mexicano del Seguro Social44 participants1 site · MexicoCompletes Aug 2026

Compare CT.gov Full analysis →

Recruiting

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

Phase 3Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8

Biospecimen CollectionBleomycin SulfateBrentuximab Vedotin+17 more

National Cancer Institute (NCI)1,875 participants407 sites · United States, Canada, Puerto RicoCompletes Apr 2031

Compare CT.gov Full analysis →

Recruiting

Phase 3Atopic Dermatitis

UpadacitinibDupilumab

AbbVie675 participants148 sites · United States, Argentina, AustraliaCompletes Jul 2030

Compare CT.gov Full analysis →

Recruiting

Rifampin-free Regimen Versus Rifampin-containing Regimen in the Treatment of Staphylococcal Prosthetic Valve Endocarditis

Phase 3Infective Endocarditis

Rifampin-free regimenRifampin containing regimen

Nantes University Hospital422 participants31 sites · FranceCompletes Dec 2030

Compare CT.gov Full analysis →

Recruiting

Comparison of Supra vs Infra Inguinal Fascia Iliaca Blocks for Spinal Positioning and Analgesia in Lower Limb Surgery

Phase 2Phase 3Post Operative AnalgesiaBradycardiaHypotension Drug-Induced

USG GUIDED SUPRA-INGUINAL FASCIA ILIACA BLOCKUSG GUIDED INFRA-INGUINAL FASCIA ILIACA BLOCK

Sahiwal medical college sahiwal60 participants1 site · PakistanCompletes Oct 2026

Compare CT.gov Full analysis →

Recruiting

DOR/TDF/3TC COmpared With BIC/FTC/TAF in ART-Naïve People Living With HIV and Overweight or Obesity

Phase 3HIV - Human Immunodeficiency VirusObesityOverweight and/or Obesity

DOR/3TC/TDFBIC/FTC/TAF

José Antonio Mata Marín306 participants1 site · MexicoCompletes Jun 2026

Compare CT.gov Full analysis →

Recruiting

Early Screening and Treatment of Heart Complication in Sickle Cell Disease

Phase 2Sickle Cell Disease

DeferoxamineDeferasiroxDeferiprone+2 more

Inova Health Care Services100 participants2 sites · United StatesCompletes Jun 2026

Compare CT.gov Full analysis →

Recruiting

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

Phase 3Heart Failure With Preserved Ejection FractionHeart Failure With Mildly Reduced Ejection FractionObesity

Maridebart cafraglutidePlacebo

Amgen5,056 participants628 sites · United States, Argentina, AustraliaCompletes Jun 2028

Compare CT.gov Full analysis →

Recruiting

Phase 3Acute Coronary Syndromes (ACS)PneumoniaCOPD (Chronic Obstructive Pulmonary Disease)

Vaxigripantibiotic treatmentspercutaneus coronary intervention

University of Brawijaya60 participants1 site · IndonesiaCompletes Aug 2026

Compare CT.gov Full analysis →

1–15 of 583