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Explore/eye disease ophthalmology retina

Status

Phase

Pre-filtered to show active, later-stage trials with the strongest clinical signal.

153 results for “eye disease ophthalmology retina” · Recruiting

Page 1 of 11

Recruiting

Intraocular Lens Power Calculation After Laser Refractive Surgery Based on Optical Coherence Tomography

N/ACataract

OCT measurements

Oregon Health and Science University690 participants1 site · United StatesCompletes Jul 2026

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Recruiting

Cholesterol and Antioxidant Treatment in Patients With Smith-Lemli-Opitz Syndrome (SLOS)

Phase 2Smith-Lemli-Opitz SyndromeCone-Rod DystrophyHearing Loss

AntioxidantsCholesterol

University of Colorado, Denver100 participants1 site · United StatesCompletes Dec 2025

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Recruiting

Spring Loaded Syringe for Active Silicon Oil Extraction

N/ARetinal Detachment

Vitrectomy machineSpring loaded syringe

Sohag University200 participants1 site · EgyptCompletes Dec 2026

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Recruiting

Ursodeoxycholic Acid (UDCA) as a Neuroprotective Adjuvant Treatment to Rhegmatogenous Retinal Detachment Surgery

Phase 3Retinal Detachment

UrsolvanPlacebo

Hopital Foch120 participants2 sites · FranceCompletes May 2027

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Recruiting

Creation of a Database of Images of the Eye With the Holographic Doppler Laser

N/AVessels of the Eye Fundus

Acquisition of images/videos of the bilateral fundus with the holographic doppler laser

Fondation Ophtalmologique Adolphe de Rothschild123 participants1 site · FranceCompletes Nov 2026

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Recruiting

Intravitreal Faricimab Injections or Fluocinolone Acetonide (0.19 mg) Intravitreal Implants vs Observation for Prevention of VA Loss Due to Radiation Retinopathy

Phase 3Radiation RetinopathyVisual Impairment

Faricimabfluocinolone acetonide

Jaeb Center for Health Research600 participants22 sites · United StatesCompletes Dec 2029

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Recruiting

Fenofibrate for Prevention of DR Worsening

Phase 3Diabetic Retinopathy

FenofibratePlacebo

Jaeb Center for Health Research560 participants66 sites · United StatesCompletes Dec 2029

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Recruiting

Vitreopapillary Interface and Optic Disc Morphology

N/APosterior Vitreous DetachmentVitreomacular TractionGlaucoma

OCT imaging/HRT imaging

Universitaire Ziekenhuizen KU Leuven350 participants1 site · BelgiumCompletes Apr 2025

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Recruiting

Arterial Spin Labeling MRI for Assessing Blood Perfusion in the Human Eye Repeatability Study and Clinical Application

N/ARetinal Diseases

MRI perfusion imaging using ASL's non-invasive technique

Cliniques universitaires Saint-Luc- Université Catholique de Louvain70 participants1 site · BelgiumCompletes Jun 2026

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Recruiting

Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD

Phase 3AMDnAMDWet Age-related Macular Degeneration

ABBV-RGX-314 Dose 1ABBV-RGX-314 Dose 2Aflibercept (EYLEA®)

AbbVie714 participants181 sites · United States, Canada, FranceCompletes Oct 2026

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Recruiting

Electrical Stimulation for the Treatment of Glaucoma

N/AGlaucomaGlaucoma, Open-Angle

Repetitive, Transorbital Alternating Current Stimulation (rtACS)Sham Repetitive, Transorbital Alternating Current Stimulation (rtACS)

Stanford University45 participants4 sites · United States, GermanyCompletes Dec 2025

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Recruiting

Intermediate Age-related Macular Degeneration - Multimodal Analysis and Longitudinal Study

N/AAge-Related Macular Degeneration

Orthoptic assessment (Outcome measure)

Universidade Nova de Lisboa150 participants1 site · PortugalCompletes Jun 2025

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Recruiting

Enhanced Vision and Imaging Tests for Enabling Treatment Trials in Early and Intermediate AMD

N/AAge - Related Macular Degeneration (AMD)

Maximilian Pfau150 participants1 site · GermanyCompletes Dec 2028

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Recruiting

Anti-vascular Endothelial Growth Factor (Anti-VEGF) Monotherapy vs Anti-VEGF Followed by Subthreshold Micropulse Laser for Treating Severe Diabetic Macular Oedema When the Central Retina Goes <400 Microns

Phase 3Severe Diabetic Macular Oedema

Subthreshold Micropulse Laser (SML)Anti-VEGF Monotherapy (standard care)

Belfast Health and Social Care Trust264 participants22 sites · United KingdomCompletes Nov 2028

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Recruiting

OCT Angiography and NRAI in Dementia

N/AAlzheimer DiseaseDementiaMild Cognitive Impairment

Optical Coherence Tomography Angiography (OCTA) ImagingNoninvasive Retinal Amyloid Imaging (NRAI)

Oregon Health and Science University20 participants1 site · United StatesCompletes Dec 2026

Compare CT.gov Full analysis →

1–15 of 153

Explore/eye disease ophthalmology retina

Status

Phase

Pre-filtered to show active, later-stage trials with the strongest clinical signal.

153 results for “eye disease ophthalmology retina” · Recruiting

Page 1 of 11

Recruiting

Intraocular Lens Power Calculation After Laser Refractive Surgery Based on Optical Coherence Tomography

N/ACataract

OCT measurements

Oregon Health and Science University690 participants1 site · United StatesCompletes Jul 2026

Compare CT.gov Full analysis →

Recruiting

Cholesterol and Antioxidant Treatment in Patients With Smith-Lemli-Opitz Syndrome (SLOS)

Phase 2Smith-Lemli-Opitz SyndromeCone-Rod DystrophyHearing Loss

AntioxidantsCholesterol

University of Colorado, Denver100 participants1 site · United StatesCompletes Dec 2025

Compare CT.gov Full analysis →

Recruiting

Spring Loaded Syringe for Active Silicon Oil Extraction

N/ARetinal Detachment

Vitrectomy machineSpring loaded syringe

Sohag University200 participants1 site · EgyptCompletes Dec 2026

Compare CT.gov Full analysis →

Recruiting

Ursodeoxycholic Acid (UDCA) as a Neuroprotective Adjuvant Treatment to Rhegmatogenous Retinal Detachment Surgery

Phase 3Retinal Detachment

UrsolvanPlacebo

Hopital Foch120 participants2 sites · FranceCompletes May 2027

Compare CT.gov Full analysis →

Recruiting

Creation of a Database of Images of the Eye With the Holographic Doppler Laser

N/AVessels of the Eye Fundus

Acquisition of images/videos of the bilateral fundus with the holographic doppler laser

Fondation Ophtalmologique Adolphe de Rothschild123 participants1 site · FranceCompletes Nov 2026

Compare CT.gov Full analysis →

Recruiting

Intravitreal Faricimab Injections or Fluocinolone Acetonide (0.19 mg) Intravitreal Implants vs Observation for Prevention of VA Loss Due to Radiation Retinopathy

Phase 3Radiation RetinopathyVisual Impairment

Faricimabfluocinolone acetonide

Jaeb Center for Health Research600 participants22 sites · United StatesCompletes Dec 2029

Compare CT.gov Full analysis →

Recruiting

Fenofibrate for Prevention of DR Worsening

Phase 3Diabetic Retinopathy

FenofibratePlacebo

Jaeb Center for Health Research560 participants66 sites · United StatesCompletes Dec 2029

Compare CT.gov Full analysis →

Recruiting

Vitreopapillary Interface and Optic Disc Morphology

N/APosterior Vitreous DetachmentVitreomacular TractionGlaucoma

OCT imaging/HRT imaging

Universitaire Ziekenhuizen KU Leuven350 participants1 site · BelgiumCompletes Apr 2025

Compare CT.gov Full analysis →

Recruiting

Arterial Spin Labeling MRI for Assessing Blood Perfusion in the Human Eye Repeatability Study and Clinical Application

N/ARetinal Diseases

MRI perfusion imaging using ASL's non-invasive technique

Cliniques universitaires Saint-Luc- Université Catholique de Louvain70 participants1 site · BelgiumCompletes Jun 2026

Compare CT.gov Full analysis →

Recruiting

Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD

Phase 3AMDnAMDWet Age-related Macular Degeneration

ABBV-RGX-314 Dose 1ABBV-RGX-314 Dose 2Aflibercept (EYLEA®)

AbbVie714 participants181 sites · United States, Canada, FranceCompletes Oct 2026

Compare CT.gov Full analysis →

Recruiting

Electrical Stimulation for the Treatment of Glaucoma

N/AGlaucomaGlaucoma, Open-Angle

Repetitive, Transorbital Alternating Current Stimulation (rtACS)Sham Repetitive, Transorbital Alternating Current Stimulation (rtACS)

Stanford University45 participants4 sites · United States, GermanyCompletes Dec 2025

Compare CT.gov Full analysis →

Recruiting

Intermediate Age-related Macular Degeneration - Multimodal Analysis and Longitudinal Study

N/AAge-Related Macular Degeneration

Orthoptic assessment (Outcome measure)

Universidade Nova de Lisboa150 participants1 site · PortugalCompletes Jun 2025

Compare CT.gov Full analysis →

Recruiting

Enhanced Vision and Imaging Tests for Enabling Treatment Trials in Early and Intermediate AMD

N/AAge - Related Macular Degeneration (AMD)

Maximilian Pfau150 participants1 site · GermanyCompletes Dec 2028

Compare CT.gov Full analysis →

Recruiting

Phase 3Severe Diabetic Macular Oedema

Subthreshold Micropulse Laser (SML)Anti-VEGF Monotherapy (standard care)

Belfast Health and Social Care Trust264 participants22 sites · United KingdomCompletes Nov 2028

Compare CT.gov Full analysis →

Recruiting

OCT Angiography and NRAI in Dementia

N/AAlzheimer DiseaseDementiaMild Cognitive Impairment

Optical Coherence Tomography Angiography (OCTA) ImagingNoninvasive Retinal Amyloid Imaging (NRAI)

Oregon Health and Science University20 participants1 site · United StatesCompletes Dec 2026

Compare CT.gov Full analysis →

1–15 of 153