ClariTrial | Search Clinical Trials

Explore/neurology CNS brain disease

Status

Phase

Pre-filtered to show active, later-stage trials with the strongest clinical signal.

158 results for “neurology CNS brain disease” · Recruiting · Phase 3 · Phase 2

Page 1 of 11

Recruiting

A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

Phase 2Phase 3Alzheimers DiseaseDementiaAlzheimers Disease, Familial

Remternetug (SC)Matching Placebo (Remternetug)

Washington University School of Medicine280 participants37 sites · United States, Argentina, AustraliaCompletes Mar 2034

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Recruiting

Communication Bridge 3 Study

Phase 2Primary Progressive Aphasia

Communication Bridge™Evidence-Based Impairment Focused

University of Chicago200 participants1 site · United StatesCompletes Jul 2028

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Recruiting

A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset Seizures

Phase 2Focal EpilepsyEpilepsyRefractory Focal Epilepsy

RAP-219

Rapport Therapeutics Inc.30 participants7 sites · United StatesCompletes Feb 2028

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Recruiting

A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease

Phase 3Parkinsons Disease (PD)

bemdaneprocelSham surgery

BlueRock Therapeutics102 participants43 sites · United States, Australia, CanadaCompletes Mar 2027

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Recruiting

A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety When Given Before Symptoms Appear in Babies With Genetically Diagnosed Spinal Muscular Atrophy (SMA)

Phase 3Muscular Atrophy, Spinal

Salanersen

Biogen30 participants11 sites · United States, Australia, BrazilCompletes Nov 2028

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Recruiting

Safinamide vs Placebo for Pain in Patients With Parkinson's Disease and Motor Fluctuations

Phase 3PARKINSON DISEASE (Disorder)PainPain Management

SafinamidePlacebo

Universita di Verona60 participants1 site · ItalyCompletes Dec 2027

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Recruiting

Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures

Phase 3Focal SeizureEpilepsyFocal Epilepsy

RAP-219RAP-219Placebo

Rapport Therapeutics Inc.312 participants11 sites · United StatesCompletes Jul 2029

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Recruiting

High Dose Steroids in Children With Stroke

Phase 3Paediatric Stroke

MethylprednisolonePrednisolone

Insel Gruppe AG, University Hospital Bern70 participants35 sites · Australia, Austria, DenmarkCompletes Jul 2026

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Recruiting

Thrombolysis in Factor Xa-inhibitors Trial

Phase 3StrokeStroke (in Patients With Atrial Fibrillation)Ischemic Stroke

thrombolysis therapy

Guri Hagberg300 participants14 sites · Denmark, NorwayCompletes Dec 2028

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Recruiting

Combination of Hypothermia and Thrombectomy in Acute Stroke

Phase 3Ischemic StrokeLarge Vessel OcclusionEndovascular Treatment

hypothermia

University of Freiburg400 participants1 site · GermanyCompletes Mar 2026

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Recruiting

Statins In Intracerbral Hemorrhage

Phase 3Intracerebral Hemorrhage

Statins

Beth Israel Deaconess Medical Center1,456 participants1 site · United StatesCompletes Dec 2028

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Recruiting

Placebo Controlled Study to Assess the Efficacy and Safety of Rapamycin in Drug Resistant Epilepsy Associated With Tuberous Sclerosis Complex

Phase 3Tuberous Sclerosis Complex

RapamycinPlacebo

Katarzyna Kotulska200 participants2 sites · PolandCompletes Jun 2027

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Recruiting

Clinical Trial on Agitation in Alzheimer's Dementia

Phase 2Alzheimer DiseaseAgitation,PsychomotorCare Giving Burden

IGC-AD1-ActiveIGC-AD1-Placebo

IGC Pharma, LLC164 participants31 sites · United States, Canada, ColombiaCompletes Aug 2026

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Recruiting

Transcranial Direct Current Stimulation for Treatment of Acute Ischemic Stroke

Phase 2Acute Ischemic Stroke

High-definition Cathodal Transcranial Direct Current Stimulation (HD C-tDCS)Sham tDCS

University of California, Los Angeles120 participants3 sites · United StatesCompletes Jan 2030

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Recruiting

A Safety and Pharmacokinetics Trial of VO659 in SCA1, SCA3 and HD

Phase 1Phase 2Spinocerebellar Ataxia Type 1Spinocerebellar Ataxia Type 3Huntington Disease

VO659

Vico Therapeutics B. V.68 participants14 sites · Denmark, France, GermanyCompletes Apr 2028

Compare CT.gov Full analysis →

1–15 of 158

Explore/neurology CNS brain disease

Status

Phase

Pre-filtered to show active, later-stage trials with the strongest clinical signal.

158 results for “neurology CNS brain disease” · Recruiting · Phase 3 · Phase 2

Page 1 of 11

Recruiting

A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

Phase 2Phase 3Alzheimers DiseaseDementiaAlzheimers Disease, Familial

Remternetug (SC)Matching Placebo (Remternetug)

Washington University School of Medicine280 participants37 sites · United States, Argentina, AustraliaCompletes Mar 2034

Compare CT.gov Full analysis →

Recruiting

Communication Bridge 3 Study

Phase 2Primary Progressive Aphasia

Communication Bridge™Evidence-Based Impairment Focused

University of Chicago200 participants1 site · United StatesCompletes Jul 2028

Compare CT.gov Full analysis →

Recruiting

A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset Seizures

Phase 2Focal EpilepsyEpilepsyRefractory Focal Epilepsy

RAP-219

Rapport Therapeutics Inc.30 participants7 sites · United StatesCompletes Feb 2028

Compare CT.gov Full analysis →

Recruiting

A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease

Phase 3Parkinsons Disease (PD)

bemdaneprocelSham surgery

BlueRock Therapeutics102 participants43 sites · United States, Australia, CanadaCompletes Mar 2027

Compare CT.gov Full analysis →

Recruiting

A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety When Given Before Symptoms Appear in Babies With Genetically Diagnosed Spinal Muscular Atrophy (SMA)

Phase 3Muscular Atrophy, Spinal

Salanersen

Biogen30 participants11 sites · United States, Australia, BrazilCompletes Nov 2028

Compare CT.gov Full analysis →

Recruiting

Safinamide vs Placebo for Pain in Patients With Parkinson's Disease and Motor Fluctuations

Phase 3PARKINSON DISEASE (Disorder)PainPain Management

SafinamidePlacebo

Universita di Verona60 participants1 site · ItalyCompletes Dec 2027

Compare CT.gov Full analysis →

Recruiting

Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures

Phase 3Focal SeizureEpilepsyFocal Epilepsy

RAP-219RAP-219Placebo

Rapport Therapeutics Inc.312 participants11 sites · United StatesCompletes Jul 2029

Compare CT.gov Full analysis →

Recruiting

High Dose Steroids in Children With Stroke

Phase 3Paediatric Stroke

MethylprednisolonePrednisolone

Insel Gruppe AG, University Hospital Bern70 participants35 sites · Australia, Austria, DenmarkCompletes Jul 2026

Compare CT.gov Full analysis →

Recruiting

Thrombolysis in Factor Xa-inhibitors Trial

Phase 3StrokeStroke (in Patients With Atrial Fibrillation)Ischemic Stroke

thrombolysis therapy

Guri Hagberg300 participants14 sites · Denmark, NorwayCompletes Dec 2028

Compare CT.gov Full analysis →

Recruiting

Combination of Hypothermia and Thrombectomy in Acute Stroke

Phase 3Ischemic StrokeLarge Vessel OcclusionEndovascular Treatment

hypothermia

University of Freiburg400 participants1 site · GermanyCompletes Mar 2026

Compare CT.gov Full analysis →

Recruiting

Statins In Intracerbral Hemorrhage

Phase 3Intracerebral Hemorrhage

Statins

Beth Israel Deaconess Medical Center1,456 participants1 site · United StatesCompletes Dec 2028

Compare CT.gov Full analysis →

Recruiting

Placebo Controlled Study to Assess the Efficacy and Safety of Rapamycin in Drug Resistant Epilepsy Associated With Tuberous Sclerosis Complex

Phase 3Tuberous Sclerosis Complex

RapamycinPlacebo

Katarzyna Kotulska200 participants2 sites · PolandCompletes Jun 2027

Compare CT.gov Full analysis →

Recruiting

Clinical Trial on Agitation in Alzheimer's Dementia

Phase 2Alzheimer DiseaseAgitation,PsychomotorCare Giving Burden

IGC-AD1-ActiveIGC-AD1-Placebo

IGC Pharma, LLC164 participants31 sites · United States, Canada, ColombiaCompletes Aug 2026

Compare CT.gov Full analysis →

Recruiting

Transcranial Direct Current Stimulation for Treatment of Acute Ischemic Stroke

Phase 2Acute Ischemic Stroke

High-definition Cathodal Transcranial Direct Current Stimulation (HD C-tDCS)Sham tDCS

University of California, Los Angeles120 participants3 sites · United StatesCompletes Jan 2030

Compare CT.gov Full analysis →

Recruiting

A Safety and Pharmacokinetics Trial of VO659 in SCA1, SCA3 and HD

Phase 1Phase 2Spinocerebellar Ataxia Type 1Spinocerebellar Ataxia Type 3Huntington Disease

VO659

Vico Therapeutics B. V.68 participants14 sites · Denmark, France, GermanyCompletes Apr 2028

Compare CT.gov Full analysis →

1–15 of 158